![]() ![]() Neurochemical imbalanceĪ neurochemical imbalance may also make neurons more likely to fire aberrantly. These can also occur as part of a genetic syndrome such as tuberous sclerosis or neurofibromatosis. Structural abnormalities in the brain affecting neurotransmission increase the risk of abnormal electrical activity and seizures. deja vu), and those involving the occipital lobe are associated with simple visual disturbance. In contrast, seizures affecting the temporal lobe are associated with experiencing abnormal sensations (e.g. pelvic thrusting, leg cycling) and vocalisation. The clinical signs of a seizure (semiology) vary depending on where it begins in the brain (the seizure focus) and where it spreads.įor example, seizures affecting the frontal lobe are associated with abnormal movements (e.g. Want discounted access to all Geeky Medics products, including our medicine flashcard collection? Check out our bundles to save money and supercharge your learning □ Aetiology PathophysiologyĮpileptic seizures result from an imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) neuronal signalling at the synaptic level, resulting in a reduced threshold for neurotransmission. ![]()
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